Nanocur FAQ

Nanocur is a pharmaceutical-developed curcumin supplement with enhanced bioavailability designed for real absorption—without black pepper extract (piperine). It uses a plant-based nanocarrier system (β-cyclodextrin) to help curcumin disperse more effectively, so your body can make better use of it.

Developed by Haus Bioceuticals using pharmaceutical drug development methods, Nanocur represents 3rd generation nanocurcumin technology optimized since 2011 by Ph.D. scientists, M.D.s, and naturopathic physicians.

Nanocur is ideal for anyone seeking bioavailable curcumin without piperine-related concerns. It's especially well-suited for:

• People taking prescription medications who want to avoid potential piperine interactions with drug metabolism
• Athletes and active individuals seeking muscle recovery support and joint comfort after exercise
• Anyone who tried curcumin before without results due to poor bioavailability
• Those wanting organic, clean-label supplements without fillers, binders, or artificial additives
• People with sensitive stomachs who find black pepper extract irritating
• Vegans and those with dietary restrictions (non-GMO, allergen-free formulation)

Nanocur is curcumin (from turmeric), not turmeric powder. Turmeric is only 2-5% curcumin, which is the main bioactive compound in turmeric. Nanocur contains organic turmeric extract standardized to 95% curcuminoids—the clinically active components.

The key difference is bioavailability, delivery technology, and pharmaceutical development approach. Standard curcumin supplements often use cheap turmeric powder, which is only 2-5% active curcumin and 95-98% inactive plant material. Nanocur delivers high bioavailable curcumin using:

• Pharmaceutical development methods – Clinical trials, preclinical modeling, and comparative effectiveness research
• Advanced nanocarrier technology – β-cyclodextrin creates water-soluble nanoparticles that help curcumin circulate more effectively
• 95% standardized curcuminoids – Organic turmeric extract, not diluted powder
• Third-party certification – Amazon/Eurofins independent verification
• No fillers or binders – Pure active ingredients only
• Piperine-free formulation – No black pepper extract

Based on preclinical models, Nanocur is 100x more active than turmeric powder and 170% more active than curcumin + black pepper formulations.

Many curcumin formulas add piperine to boost absorption—but some people prefer to avoid it. Piperine works by inhibiting certain drug-metabolizing enzymes (particularly in the liver) and transporters, which can:

• Interfere with how your body processes prescription medications
• Potentially cause buildup of common medications and toxins
• Slow curcumin metabolism (which some view as beneficial, but has tradeoffs)
• Cause digestive discomfort in sensitive individuals

If you take prescription medications—or just want a piperine-free option—Nanocur uses a plant-based carrier system instead of piperine for enhanced absorption.

Nanocur focuses on advanced delivery—not inhibiting liver processing with black pepper extract. Instead of adding piperine, Nanocur uses a plant-based nanocarrier (β-cyclodextrin) designed to help curcumin disperse more effectively.

• Piperine-free (no black pepper extract, no BioPerine®)
• Organic turmeric extract standardized to 95% curcuminoids
• Water-soluble nanoparticle technology for better circulation and absorption
• Can be mixed into drinks – Naturally earthy, slightly sweet flavor when used directly in food or drinks

Nanocur represents 3rd generation nanocurcumin technology using β-cyclodextrin delivery with pharmaceutical development and clinical validation. While Longvida, Meriva, and BCM-95 are established branded curcumin formulations with their own delivery systems:

• Longvida uses lipid (fat) coating technology
• Meriva uses lecithin (Phytosome) technology
• BCM-95 uses turmeric essential oils and no piperine
• Nanocur uses plant-based soluble fiber (β-cyclodextrin) nanocarrier technology

Unique to Nanocur:

• Head-to-head preclinical testing showing superior activity vs. these brands
• Human clinical trials (Type 2 diabetes, gestational diabetes)
• Amazon/Eurofins third-party certification
• Pharmaceutical development approach with over a decade of R&D

All aim to improve curcumin bioavailability through different mechanisms. Nanocur's approach creates 5 nM soluble fiber nanocurcumin complexes and is specifically piperine-free.

"NanoCur®" refers to Nanocur's delivery approach, designed to make curcumin easier for the body to use. The technology creates water-soluble nanoparticle shells that encapsulate water-insoluble curcumin molecules, helping them:

• Better assimilate and circulate throughout the bloodstream
• Reach tissues, organs, and cells more effectively
• Achieve higher bioavailability than standard curcumin powder

Translation: the goal is to help curcumin perform better than standard powders that don't disperse well in the body.

These claims are based on direct comparative testing in preclinical disease models—not theoretical calculations.

The activity claims come from standardized testing where:

• 100x more active than turmeric – Comparing Nanocur's bioavailable curcumin to raw turmeric powder (which is only 2-5% curcumin and poorly absorbed) in the same preclinical model
• 170% more active than curcumin + black pepper – Comparing Nanocur's nanocarrier technology to standard curcumin with piperine formulations in head-to-head testing

These results have been validated across multiple disease models including:

• Diabetes (streptozotocin model)
• COVID-19 viral replication (in vitro)
• Rheumatoid arthritis
• Inflammatory bowel disease

Important context: These are preclinical laboratory results demonstrating formulation performance, not guaranteed personal outcomes. Your results depend on your body, consistency, and personal goals. We recommend tracking your results and optimizing your dose to maximize benefits over time.

β-cyclodextrin is a plant-based soluble fiber that acts as a "carrier" for curcumin. Think of it as a very small (5nm) protective shell around a curcumin molecule that:

• Makes water-insoluble curcumin water-soluble (~1,000x higher solubility)
• Protects curcumin during digestion
• Helps curcumin molecules disperse and circulate more effectively
• Is non-toxic, natural, and supports gastrointestinal health

This is Nanocur's proprietary plant-based soluble fiber nanotechnology that maximizes curcumin absorption without piperine. The technology is detailed in Haus Bioceuticals' patent application for "Compositions and Methods for Increasing Bioavailability using Cyclodextrin Modification."

Yes, the β-cyclodextrin delivery technology used in Nanocur is the subject of a published patent application. The patent application, "Compositions and Methods for Increasing Bioavailability using Cyclodextrin Modification" (WO2023023648A1), describes the innovative manufacturing process and delivery system that makes Nanocur's enhanced bioavailability possible.

This patent-pending technology represents over a decade of research by Haus Bioceuticals' team of Ph.D. scientists, M.D.s, and naturopathic physicians. View the patent application

Nanocur is developed using pharmaceutical drug development methods—not typical supplement formulation. Haus Bioceuticals, the company behind Nanocur, uses an evidence-based nutraceutical development approach that results in supplements with pharmaceutical-grade development and exceptional safety.

This pharmaceutical approach includes:

• Comprehensive preclinical modeling – Testing in disease models to optimize formulation and dosing
• Human clinical trials – Evaluating efficacy and safety in actual patients
• Mechanism of action studies – Understanding how the formulation works at a molecular level
• Comparative effectiveness research – Direct testing against competitor products and standard treatments
• Rigorous third-party testing – Independent verification of purity, potency, and safety

This R&D approach is uncommon for dietary supplements because it's expensive and requires the clinical research expertise of the Ph.D. scientists, M.D.s, and naturopathic physicians who founded and run Haus Bioceuticals. Learn more about the research team .

Yes, Nanocur has been evaluated in both preclinical disease models and human clinical trials.

Preclinical Studies:

• Rheumatoid arthritis (collagen-induced arthritis model)
• Inflammatory bowel disease (Crohn's/ulcerative colitis models)
• Alzheimer's disease
• Parkinson's disease
• COVID-19 antiviral activity (in vitro)
• Type 2 diabetes (streptozotocin model)

Human Clinical Trials:

• Type 2 Diabetes Proof-of-Concept Study (n=17) – 7-week open-label clinical research study. Study participants showed favorable changes in blood glucose measurements throughout the study period. No treatment-related adverse effects observed. Study results supported the technology development and formulation optimization.
• Gestational Diabetes Mellitus Study (n=8) – 44-week prospective study exploring curcumin's role in maternal metabolic health. Study participants showed favorable blood glucose measurements throughout pregnancy. No treatment-related adverse effects. All participants had healthy pregnancies and babies. Blood glucose measurements remained in favorable ranges without hypoglycemic events.

Important disclaimer: These clinical studies were conducted to validate the technology and formulation. Nanocur is marketed as a dietary supplement, not a drug, and is not intended to diagnose, treat, cure, or prevent any disease. These results demonstrate the pharmaceutical-grade development approach used to create Nanocur.

In preclinical comparative effectiveness studies, Nanocur demonstrated higher activity than leading bioavailable curcumin brands.

In a standardized diabetes model (streptozotocin-induced diabetes in C57BL/6 mice, detailed in patent application US20240350660A1), Nanocur's β-cyclodextrin technology was tested head-to-head against established bioavailable curcumin formulations:

In COVID-19 in vitro studies testing viral titer reduction, Nanocur demonstrated:

• 20x higher activity than standard turmeric
• 2x higher activity than typical bioavailable curcumin formulations
• 62% higher activity than popular high-bioavailability curcumin brands

Important context: These are preclinical laboratory results demonstrating formulation performance in research models, not clinical outcomes in humans. The comparative studies validate Nanocur's delivery technology and are consistent with its enhanced bioavailability design. Individual results may vary.

Nanocur undergoes pharmaceutical-grade manufacturing and rigorous third-party testing that exceeds typical supplement standards.

Amazon Third-Party Certification (Eurofins Verified):

Nanocur has passed Amazon's mandatory third-party certification program, one of the most rigorous verification systems in the supplement industry. This certification is:

• Conducted by Eurofins – One of only 3 labs worldwide authorized by Amazon (alongside NSF and UL)
• Independently verified – Test results go directly from Eurofins to Amazon; manufacturers cannot alter data
• Mandatory for all Amazon supplements – Required as of April 2024
• Annually renewed – Products must be re-verified every 12 months to remain on Amazon
• Comprehensive testing – 7 critical safety categories required

What Nanocur Passed:

Certificate of Analysis Report: 5102972-0 | Status: PASSED | Valid Through: October 2026

Why this matters: Unlike typical supplement testing where brands self-report results, Amazon's program requires direct lab-to-Amazon reporting with zero manufacturer manipulation. This provides independent, forensic-level verification that many supplements cannot achieve. Amazon implemented this program in 2024 after FDA warning letters exposed widespread issues with counterfeit, adulterated, and mislabeled supplements.

The pharmaceutical development approach used for Nanocur is too expensive and sophisticated for most supplement companies.

Typical supplement development:

• Companies select ingredients from scientific literature
• Combine them without optimization or testing
• Results in non-optimized efficacy, potential safety issues, unforeseen ingredient interactions, and suboptimal dosing
• This is where most companies stop

Haus Bioceuticals' pharmaceutical approach requires:

• Extensive preclinical modeling in disease models (rheumatoid arthritis, diabetes, IBD, Alzheimer's, etc.)
• Candidate screening and ratio optimization
• Comparative effectiveness testing vs. competitors
• Dose-ranging studies
• Human clinical trials (Type 2 diabetes, gestational diabetes)
• Supply chain optimization based on activity testing
• Rigorous third-party certification (Amazon/Eurofins)
• World-class research team (Ph.D. scientists, M.D.s, naturopathic physicians)

This process takes years and significant R&D investment, but results in supplements with pharmaceutical-grade activity and exceptional safety. Haus has been optimizing curcumin bioavailability since 2011—over a decade of dedicated research resulting in published patent applications and clinical validation.

Active complex (proprietary): β-cyclodextrin (plant-based carrier) + organic turmeric extract (standardized to 95% curcuminoids).

Other ingredient: hypromellose (vegan capsule, also called hydroxypropyl methylcellulose).

Verified potency: 169mg total curcuminoids per serving (2 capsules), confirmed by Eurofins UPLC testing.

Serving size is 2 vegan capsules, providing 1300 mg of the NanoCur® proprietary complex with 169mg curcuminoids (independently verified). Because it's a proprietary complex, the label lists the combined amount of the β-cyclodextrin carrier and organic turmeric extract together. The turmeric extract is standardized to 95% curcuminoids, and the actual curcuminoid content has been verified by Eurofins laboratory testing.

Yes, Nanocur uses organic turmeric extract standardized to 95% curcuminoids. If "organic" is important to you, always confirm on the label of the exact bottle you receive.

Yes, Nanocur uses a vegan capsule (hypromellose) and is non-GMO. It's also free from soy, milk, eggs, peanuts, shellfish, and wheat.

Yes, Nanocur is produced under current Good Manufacturing Practices (cGMP) and has passed Amazon/Eurofins third-party certification. This includes:

• GMP facility verification (FDA 21 CFR 111 compliance)
• Adulterant screening (12+ pharmaceutical compounds tested, all NOT DETECTED)
• Heavy metals testing (all passed with large safety margins)
• Pathogen testing (Salmonella, E. coli, Staph aureus - all absent)
• Microbiological testing (passed all counts)
• Label accuracy verification (169mg curcuminoids confirmed)

Certificate of Analysis: 5102972-0 (valid through October 2026). This independent verification cannot be manipulated by the brand—test results go directly from Eurofins to Amazon.

Suggested use: adults take 2 capsules in the morning, or as directed by your healthcare professional. Many users with chronic issues take 2 capsules in the morning and 1-2 capsules in the afternoon for sustained support.

Consistency matters: taking it at the same time daily makes it easier to notice patterns and establish a routine. The optimal dose used in clinical trials was approximately 25 mg/kg body weight.

You can take Nanocur with or without food. If you're sensitive to supplements, taking it with a meal and water can feel gentler on your stomach. Many users report it doesn't upset their stomach like other supplements.

Yes—if swallowing capsules is a challenge, you can open a capsule and mix it into water, juice, or a smoothie. The soluble fiber nanocurcumin complex has a naturally earthy, slightly sweet flavor. Many people describe it as pleasant and easy to incorporate into drinks.

Pro tip: blend it into a smoothie for the easiest experience. The water-soluble formulation disperses well in liquids.

Because Nanocur's enhanced bioavailability means curcumin reaches peak blood levels within 1-2 hours, timing can be optimized based on your goals.

Strategic timing options:

• Morning (most popular): Take upon waking to support energy and mental clarity throughout the day. Peak levels occur during your active hours.
• Pre-workout: Athletes often take 1-2 hours before exercise to have curcumin at peak levels during activity and recovery.
• Split dosing: Take 2 capsules in morning, 1-2 in afternoon for sustained coverage. Provides two absorption peaks throughout the day.
• As needed: Some users take Nanocur when they anticipate needing support (before long workouts, busy days, etc.) due to the rapid absorption timeline.

Choose a time you'll remember consistently—routine matters more than perfect timing. The optimal dose used in clinical trials was approximately 25 mg/kg body weight.

Many adults use curcumin as part of a daily wellness routine. Use only as directed on the label and consult a clinician if you plan long-term use—especially if you take medications or have a medical condition. In research studies, the formulation was evaluated daily for 7 weeks (Type 2 diabetes research) and up to 44 weeks (gestational diabetes research) with no adverse effects reported.

Generally, curcumin can be taken alongside most common supplements like fish oil, vitamin D, magnesium, and multivitamins.

If you have specific concerns or take therapeutic doses of other supplements, consult your healthcare provider for personalized guidance.

Nanocur is designed to support a healthy inflammatory response and whole body wellness. Many customers choose it to support:

• Joint comfort & mobility – Ease of movement and reduced discomfort
• Muscle comfort after activity – Post-exercise recovery and athletic performance
• Cognitive health – Memory, focus, and mental clarity
• Cardiovascular health – Heart and circulatory system support
• Metabolic health – Supporting healthy metabolism (demonstrated in clinical trials)
• Antioxidant support – Protection against oxidative stress for healthy aging
• Multisystem support – Brain, liver, prostate, bone, blood, and heart

These are structure/function support statements—not disease treatment claims. The scientific literature on bioavailable curcumin's effects is extensive with over 13,000 peer-reviewed articles. For clinical studies and research on curcumin bioavailability, visit our Science page .

Nanocur's enhanced bioavailability means curcumin reaches peak blood levels within 1-2 hours—significantly faster than standard curcumin formulations.

What users report:

• Within first few hours: Many users notice improved energy and mental clarity
• First week: Common reports of better focus, reduced morning stiffness, improved recovery after exercise
• Weeks 2-4: Progressive support for joint comfort and overall wellness
• Month 1+: Cumulative benefits across multiple body systems

In research studies:

• Pharmacokinetic data shows rapid absorption with peak levels at 1-2 hours
• Research participants in Type 2 diabetes studies showed measurable changes within 1 week
• Gestational diabetes research participants showed favorable outcomes throughout the study period

Individual experiences vary based on consistency, dosage, body chemistry, and personal health status. Many verified purchasers on Amazon mention noticing effects within hours of first use, particularly related to energy and mental clarity. For sustained benefits, consistent daily use is recommended.

Most customers report the capsules are easier to swallow than previous supplements they've tried. The vegan capsules are standard size. If swallowing capsules is difficult for you, you can open them and mix the contents into a drink (see FAQ above).

This refers to Nanocur's fast-acting bioavailable formulation compared to standard curcumin or turmeric powder. Because the nanocarrier technology enhances absorption, users may experience benefits more quickly than with poorly absorbed formulations. Clinical trial data shows measurable effects within 1 week of consistent use.

Yes, extensive clinical research demonstrates that bioavailable curcumin formulations deliver measurable benefits. Studies show that when absorption barriers are overcome through advanced delivery systems, curcumin supports:

• Joint comfort and mobility (randomized controlled trials)
• Cognitive function and memory (meta-analyses)
• Metabolic health and glucose balance (clinical trials including Nanocur's Type 2 diabetes study)
• Cardiovascular function and arterial health (systematic reviews)
• Post-exercise muscle recovery (recent 2025 studies)

Our Science page provides a comprehensive research library with links to peer-reviewed studies on PubMed and other scientific databases. These studies examine the active ingredient (curcumin) when bioavailability barriers are addressed through various advanced formulations. The scientific literature includes over 13,000 peer-reviewed articles on curcumin's clinical potential.

Curcumin supplements are generally well tolerated, but some people may be sensitive or allergic to curcumin. Many users report Nanocur is easier on their stomach than other supplements.

In clinical trials:

• Research study (n=17): No treatment-related adverse effects, no hypoglycemic events observed during safety monitoring
• Maternal health research study (n=8): No treatment-related adverse effects, healthy pregnancy outcomes
• Dose-ranging studies: Some headaches reported at higher doses

If you feel uncomfortable, stop use and consult a healthcare professional. Turmeric is GRAS (Generally Recognized as Safe), and curcumin has shown no dose-limiting toxicity at doses up to 12 g/day in human dose escalation studies.

If you take prescription medications, talk with your clinician first before taking any curcumin supplements. This is especially important if you use:

• Blood thinners/anticoagulants (e.g., warfarin, aspirin, Plavix)
• Diabetes medications (research studies observed changes in blood glucose measurements)
• Medications metabolized by the liver

Also consult your doctor if you have upcoming surgery or manage a chronic condition. Note that Nanocur is piperine-free, which eliminates the enzyme inhibition concerns associated with black pepper extract that can interfere with drug metabolism.

Ask your healthcare professional first. Always consult with your obstetrician or midwife before taking any supplement while pregnant or nursing.

Note: Nanocur was safely used in a gestational diabetes study (n=8, 44 weeks) with no adverse effects and healthy outcomes. However, this was conducted under medical supervision in a clinical trial setting. Individual circumstances vary, so professional medical guidance is essential.

Formulas with black pepper extract can inhibit certain drug-metabolizing enzymes (particularly in the liver) and transporters, which can affect liver function.

High-dose turmeric supplements can cause kidney toxicity primarily due to soluble oxalates. Nanocur does not contain black pepper extract or bulk turmeric powder. The process of purifying 95% curcuminoids also removes oxalates from turmeric.

In clinical research studies:

• No liver-related adverse effects observed
• No kidney-related adverse effects observed
• Used safely for up to 44 weeks under medical supervision

If you notice any adverse medical issues from a supplement, like an allergic reaction, stop use immediately and contact a healthcare professional. If you have existing medical conditions or concerns, consult your doctor before starting any curcumin supplement.

It's the same formula—just a different supply length. Since the serving size is 2 capsules per day:

• 90-count bottle = 45-day supply
• 180-count bottle = 90-day supply (3 months)

Many customers prefer the 180-count for better value and fewer reorders.

If bioavailability and clinical validation matter to you, Nanocur delivers significantly more value than regular turmeric. Consider:

• Regular turmeric powder is only 2-5% curcumin and poorly absorbed
• Standard curcumin supplements often contain fillers and may require higher doses
• Nanocur delivers pharmaceutical-grade curcumin with:
  • Advanced nanocarrier technology (patent-pending)
  • Human clinical trial validation
  • Preclinical testing showing superiority vs. competitors
  • Amazon/Eurofins third-party certification
  • Over a decade of pharmaceutical R&D

You're paying for quality ingredients, 3rd generation technology, clinical evidence, and independent verification. Many users report this is the first curcumin supplement they actually felt working.

Golden paste and homemade turmeric drinks can be great, but they face bioavailability challenges. Key differences:

• Consistency: Nanocur provides standardized 95% curcuminoids in every dose; homemade preparations vary widely
• Bioavailability: Raw turmeric is poorly absorbed even with black pepper and fats; Nanocur's nanocarrier technology dramatically enhances absorption (demonstrated in clinical trials)
• Convenience: No measuring, mixing, or cleanup—just 2 capsules daily
• Piperine-free: If you want to avoid black pepper for medication interaction reasons, Nanocur offers an alternative
• Clinical validation: Human trials showing actual benefits, not just traditional use

Both approaches can have value. If you enjoy making golden paste, you might also benefit from Nanocur for consistent, therapeutic-level support backed by clinical evidence.

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